Androgen Deficiency and Testosterone Replacement: Current by Craig F. Donatucci MD (auth.), Wayne J.G. Hellstrom (eds.) PDF

By Craig F. Donatucci MD (auth.), Wayne J.G. Hellstrom (eds.)

ISBN-10: 1627031782

ISBN-13: 9781627031783

ISBN-10: 1627031790

ISBN-13: 9781627031790

Androgen Deficiency and Testosterone substitute: present Controversies and Strategies explores the problems round the prognosis and remedy of androgen deficiency. The textual content examines the on hand proof in regards to the prognosis and therapy of guys with low testosterone. It additionally examines controversies within the identity and administration of those males. whereas the knowledge contained inside can be of use to people who focus on androgen deficiency and sexual medication, the scope of the e-book will function a resource of easy information regarding testosterone substitute and as a resource of reasoned research of the controversies surrounding testosterone substitute within the getting older male. Physicians and health care professional extenders could be capable of practice proof administration ideas to the overview and remedy of fellows with testosterone deficiency; supported via the latest perform guidance to be had. The authors symbolize a decide on crew of physicians with services in androgen deficiency and alternative.

Androgen Deficiency and Testosterone substitute: present Controversies and Strategies should be of serious worth to all physicians and health professional extenders who bring well-being care to males of every age.

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Additional info for Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies

Sample text

Calculation of Free Testosterone Free testosterone can be calculated based on the concentration of SHBG, albumin, and total testosterone. Several different calculations for free T have been described in the literature [33]. These equations require the use of equilibrium dissociation constants for the binding of SHBG and albumin to testosterone, which are usually defined as 1 × 109 and 3 × 104 L/M, respectively. These numbers are not universally agreed upon, which can lead to discrepant results when the equations are compared [33].

Five studies showed no change and two studies revealed a negative impact of treatment. The generic tools performed poorly when evaluated for clinical face validity. They only performed better than specific tools in regards to incorporating a global rating separate from other domains. General HRQoL questionnaires are useful to compare across populations or between different disease states. They can also augment the utility of disease-specific measures to make the findings applicable across a wider patient population.

8. Wu FCW, Tajar A, Beynon J, et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Eng J Med. 2010;363:123–35. 9. Feldman HA, Longcope C, Derby CA, et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. Clin Endocrinol Metab. 2002;87:589–98. 10. Gray A, Feldman HA, McKinlay JB, Longcope C. Age, disease and changing sex hormone levels in middle-aged men: results of the Massachusetts male aging study.

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Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies by Craig F. Donatucci MD (auth.), Wayne J.G. Hellstrom (eds.)


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